Research Articles
Inferring Microbial Dynamics: A Practical Guide to Granger Causality for Time Series Microbiome Networks
This article provides a comprehensive framework for applying Granger causality to infer directed interaction networks from longitudinal microbiome data.
Unveiling the Microbiome Network: A Comprehensive Guide to Gaussian Graphical Models for Microbial Interaction Analysis
This article provides a detailed guide to Gaussian Graphical Models (GGMs) for inferring microbial interaction networks from high-throughput sequencing data.
Zero-Inflated Generalized Poisson Factor Analysis with GLMs: A Powerful Tool for Modern Drug Discovery and Biomarker Research
This article provides a comprehensive guide to GLM-based Zero-Inflated Generalized Poisson Factor Analysis (ZIGPFA), a sophisticated statistical framework designed for high-dimensional count data with excess zeros, prevalent in modern biomedical...
Longitudinal Microbiome Analysis with GEE-CLR-CTF: A Comprehensive Guide for Biomedical Researchers
This article provides a comprehensive guide to the GEE-CLR-CTF model, a sophisticated statistical framework for analyzing longitudinal microbiome data.
Beyond the Zeros: Advanced Filtering Strategies for Zero-Inflated Microbiome (OTU) Data Analysis
This article provides a comprehensive guide for researchers and bioinformaticians tackling the pervasive challenge of zero-inflation in Operational Taxonomic Unit (OTU) tables.
Faith's Phylogenetic Diversity (PD) Explained: Definition, Calculation, and Applications in Biomedical Research
This article provides a comprehensive guide to Faith's Phylogenetic Diversity (PD), a cornerstone metric in biodiversity science with growing importance for drug discovery and microbiome research.
FTA Cards for Fecal Sample Storage: A Complete Guide to Room Temperature Biobanking for Researchers
This comprehensive guide explores the application of Flinders Technology Associates (FTA) cards for the stabilization and room-temperature storage of fecal samples.
Controlling False Discoveries in Longitudinal Data: A Comprehensive Guide to FDR Correction for Researchers
This article provides a comprehensive guide to applying False Discovery Rate (FDR) correction in longitudinal analysis for biomedical researchers and drug development professionals.
Simulating Truth: A Rigorous Framework for Assessing FDR Control Accuracy in Microbiome Differential Abundance Analysis
This article provides a comprehensive guide for researchers evaluating False Discovery Rate (FDR) control in microbiome differential abundance testing.
Powering Discovery: A Comprehensive Guide to Evident Software for Microbiome Research and Clinical Trials
This article provides a complete roadmap for researchers, scientists, and drug development professionals utilizing Evident software for microbiome study power analysis.